Modafinil: Online Guide to the World's Safest Smart Drug


There’s been a lot of hype going on in recent years about Modafinil and its efficacy as a cognitive enhancer.


Nowadays, many people prefer to buy Modafinil online rather than go to the doctor for a prescription.


The 2011 movie Limitless saw the rise of nootropics in the online space, with Modafinil being regarded as the closest thing to the real-life Limitless pill.


While it won’t give you superpowers, it’s been hailed by many users as a life-changing solution for a more meaningful life.


On top of that, it’s been found to be safe and non-addictive, as also stated in countless user reports. [1]



Understanding Modafinil


Initially, it was designed to treat sleep-related disorders such as narcolepsy or obstructive sleep apnea.[2][3]


Off-label use has been increasing, and there are more healthy people taking it than those who are suffering from medical conditions.


The competitive world in which we live in is quite apparent, and more and more people are looking to gain an edge.


Students are looking for substances that help them get higher grades rather than get high.


Professionals looking to get ahead at work are using it to stay on top of their game at will.


The list can go on..


Buying Modafinil online vs. Getting it via prescription


Modafinil can be acquired via prescription, though it may be tricky to do so if you’re completely healthy.


Most users have acquired their Modafinil from online vendors that are usually based in India.


There are some Modafinil vendors that are worth ordering from and others to stay away due to their shady way of conducting business.


Before examining the online environment surrounding Modafinil, let’s examine the substance itself from a scientific point of view, as well as a subjective one after studying several online user experiences.


The science behind Modafinil


Modafinil is part of the eugeroic (wakefulness-enhancing) class of substances. It’s FDA-regulated and can be obtained through a prescription from your doctor, or by ordering it from online pharmacies.


Modafinil’s mechanism of action is quite complex, as it modulates a significant number of neurotransmitters. It affects norepinephrine, serotonin, dopamine, glutamate, histamine, orexin and GABA.[4]


Dopamine receptors are blocked by Modafinil and this deters dopamine uptake, leading to increased availability in the brain. Modafinil also activates the D1 and D2 receptors, which is why users experienced increased drive, motivation and a boost in imagination (as several studies have indicated).


The increase in norepinephrine also contributes to the wakefulness experienced while on Modafinil. Still, one study has shown that the wakefulness and stimulatory effects of Modafinil weren’t diminished. [5]


As shown in several animal studies, histamine is increased through neurons that release orexin, which are also stimulated by Modafinil. Both neurotransmitters play a key role when it comes to wakefulness. Orexin also produces stimulatory effects.[6][7]


Glutamate (the main excitatory neurotransmitter) is increased while GABA (the main inhibitory neurotransmitter) is decreased. Still, the exact mechanism of action is not known when it comes to these two neurotransmitters, as there are a number of contradicting study results. [8]


Modafinil vs Adderall and other stimulants


Modafinil doesn’t fall into the stimulant category, yet it can be more effective than any of them.


Many people start using Modafinil because they want a cleaner way to stay on top of their game when confronted with difficult days or lack of sleep the night before.


Modafinil vs Adderall – Modafinil is seen as a safe and effective alternative to Adderall. Its addictive potential is almost non-existent, although one may enjoy the vigilant state and want to experience it on a regular basis.

Its lack of euphoria makes its potential for abuse significantly lower than Adderall.

Even though Modafinil is less potent than Adderall, the level of cognitive enhancement is similar to Adderall and its side effects are much lower.


Modafinil vs caffeine – Many nootropic users compare Modafinil to a stronger cup of coffee. While the effects are comparable, caffeine is much less effective when it comes to warding off cognitive impairment caused by lack of sleep. Also, caffeine causes jitteriness and there’s a thin line between consuming the right amount and experiencing uncomfortable, stimulant—specific side effects that occur from high doses.


Modafinil vs methylphenidate – The cognitive enhancement felt on methylphenidate (Ritalin) is similar in potency and parts of cognition that are influenced. Still, even in this case, once you’ve gone over that fine line, the effects can be considered somewhat recreational.

Off-label use of Modafinil (online user reports and scientific studies)


Modafinil doesn’t fall into the stimulant category, yet it can be more effective than any of them.


Anti-laziness wonder

Modafinil’s effects on motivation, mood and energy levels make it ideal for accomplishing work-related tasks, as well as keeping up with one’s previously set goals. As long as you’re in the right mindset, getting started and keeping on going becomes significantly easier.

As you may or may not know, willpower is a limited resource, and a typical work day can leave one mentally fatigued when arriving home. Modafinil basically recharges one’s battery and boosts confidence. Say goodbye to laziness!


Awake and alert

The increase in norepinephrine levels mostly accounts for the alert state felt while on Modafinil. Dopamine, orexin and histamine also play a role in increasing wakefulness and alertness.

The subtle modulation of the mentioned neurotransmitters produces stimulatory effects which are encouraged, rather than forced (as seen in other stimulants such as Adderall or Ritalin).

Still, even a small dose is effective in increasing one’s ability to stay alert and switch from one task to another. Also, Modafinil is effective in helping the mind function at full capacity when deprived of sleep.

Nighttime workers are prone to suffering shift work sleep disorder, a circadian rhythm health issue that causes sleepiness during times when one should be focused, and insomnia when one should be sleeping. Modafinil has been found to help nighttime workers be more active during working hours, which in turn helps them sleep by making them more mentally drained by the end of the day.

Those suffering from sleepiness caused by depression or Parkinson’s disease have also been found to benefit from Modafinil’s wakefulness-enhancing effects. Last but not least, one of the most common off-label uses for Modafinil is for attention-deficit hyperactivity disorder.


Improved mood

Serotonin and dopamine are the two neurotransmitters that are responsible for the smart drug’s positive effects on mood.

Studies performed on humans have proven that the amygdala (which is responsible with anxiety) becomes less prone to react to threatening stimuli.

Still, many people report feeling irritable and anxious after taking Modafinil.

Interestingly, a study performed on teenagers found that 100 mg doses actually increased stress and anxiety, while doses of 200 mg have been shown to decrease anxiety. [https://www.ncbi.nlm.nih.gov/pubmed/12672167]


Accelerated body and mind

Modafinil improves reaction times both mentally and physically, which can definitely benefit those practicing competitive activities such as sports or computer games.

Modafinil makes it easier to accomplish tasks which require complex problem-solving and attention-switching. Reading speed is also increased.

Improvements are obvious when it comes to physical endurance, as well as the will necessary to give it all during a competition or a sport.

This has caused the World Anti-Doping Agency to prohibit the use of Modafinil during sports events.[8]


Side effects of Modafinil (and how to minimize them)


Potency and complete lack of side effects is never a possible feat. Some side effects of Modafinil are subtle and a natural effect of certain neurotransmitters being affected, while others may be a cause for concern.[9]


If you experience severe dizziness, agitation, nausea or allergic reactions that don’t go away after a short amount of time, you should let your physician know immediately.


The most common side effects are as follows:


Jaw clenching – This typically manifests itself in a subtle way, especially when compared to stimulants. Chewing gum will help in case it becomes uncomfortable.


Dehydration – Almost any substance that stimulates you will cause your body to need more water in order to stay properly hydrated. Not drinking enough water will result in dry mouth and headaches. Always have water nearby, as you may find yourself glued to the chair for hours in deep focus. Also, eating fruit before and during the experience also helps.


Headaches – Sometimes, people taking Modafinil experience headaches, although most of the time this occurs due to insufficient water intake.


Anxiety – Increased levels of norepinephrine exacerbate the fight-or-flight response. This is beneficial up to the point in which you begin to feel uncomfortable. You should avoid consuming caffeine or any other stimulant. Also, certain adaptogens such as Ashwagandha or Bacopa Monnieri help take the edge off.



What to look out for when buying Modafinil online


In spite of it being a prescription-only drug in most parts of the world, the online world of Modafinil has been growing in recent years.


This lead to more and more vendors appearing as demand has been increasing. Some vendors have proven their reliability in the face of difficult business, others have ceased their business for varying reasons.


While it’s always best to stick to established vendors, here are a few telltale signs of an untrustworthy vendor so that you can avoid being scammed:


Website – A shady-looking design is a sign of not paying attention to quality. An incomplete website is a surefire sign of unprofessionalism, which should make you question whether you’re willing to trust with your order. The TOS (Terms of Service) and Privacy Policy pages are mandatory for any e-commerce website.


Reputation – Even though fake reviews are popular in just about any niche, there are some instances where it’s quite obvious that the review is genuine. Sites like Reddit or Longecity feature awesome communities with active users that wouldn’t randomly post fake comments. Still, it’s always best to check their profile and have your “b*****it meter” on.


Price – Newer vendors may price their Modafinil 10 – 15 % lower than other more popular vendors. If you see ridiculous prices that are too good to be true, you’d better believe they aren’t..


Refund/reshipment policy – Some vendors are willing to take the risk of border seizure upon themselves and provide reshipment or refund if the order doesn’t arrive for that reason.


Ordering Modafinil around the world


Modafinil is an FDA-regulated schedule IV substance in the USA. It’s widely available in many countries across the world as a prescription drug.


Some countries have laws which are more relaxed and that’s where most Modafinil vendors conduct their business from.


One common misconception about Modafinil is its legality.


Possession, as well as purchasing it online aren’t prosecuted and you can safely buy it online from reliable Modafinil pharmacies.


Worst case scenario would be that border control sends you a letter inviting you to come and claim the Modafinil with your prescription.


You can easily choose not to go, and they will simply throw away your order after a while.


Steps to take when buying Modafinil online


Choose a reputable Modafinil vendor – With so many online Modafinil vendors to choose from, it can be daunting to make a decision. Reputation and high Google rankings don’t always guarantee reliability. In fact, ModaPharma has gained widespread fame in 2018 for the many complaints that are circulating across the web regarding fake tabs and undelivered orders.


BuyXArmodafinil.org, for example, is a new player on the market, and it’s run by a team of Americans. Their responsive live chat is definitely a defining factor for their recent rise in the Modafinil online biz.


(Optional, but recommended) Buy Bitcoin – Most Modafinil vendors offer considerable Bitcoin discounts of 10-20%. One popular Bitcoin wallet service is Blockchain.info. Most reliable pharmacies offer other methods of payment including credit card, PayPal and wire transfer.


Choose a brand (or more) – Waklert, Artvigil, Modalert and Modvigil are the four most popular brands of Armodafinil and Modafinil, respectively. There are some slight differences between the four brands, particularly between Armodafinil and Modafinil.


(Optional) Go for a mail forwarding service – People are opting for a mail forwarding service due to decreased likelihood of having the order seized by border control. If you live in a country with rigorous border control, using such a service is necessary. Users from Reddit, Longecity or Quora recommend Skypax.



How much does Modafinil cost?


The generic brand that doctors prescribe can be VERY expensive. It ranges between 700 – 1000 $ for a 30 tablet pack.


No wonder that people are ordering it online.. If your insurance plan doesn’t cover it, it’s just too expensive, even for a middle-class American citizen.


Brands like the ones manufactured by HAB Pharma (Modvigil, Artvigil) or Sun Pharma (Modalert, Waklert) have prices that range between 2.8$ and 0.97$.


Most reputable vendors that are worth ordering from offer cryptocurrency discounts and some even offer discounts for returning customers.


On top of that, some vendors also offer free shipping.



Should you use Modafinil?


Whether or not you should be using Modafinil depends on why you're planning to do so.


Modafinil is in no way a recreational drug, as some people may assume.


It won't get you high.. Some people might say that it does quite the opposite.


Modafinil is great for productivity, studying, performance-enhancement and some health problems (depression, ADHD, sleep disorders).


If you intend on using it for recreational purposes, then you should seriously reconsider.


Modafinil has so much to offer when it comes to the more meaningful parts of life.


Its potency, safety and low addictive potential make it the best choice for a "Carpe Diem" mindset.


Getting a prescription can be tricky, and even then, the price of generic Modafinil (Provigil) is ridiculous.


Hence, people choose to buy Modafinil online from the many pharmacies that mostly operate from India.


Even then, though, you should consult your doctor beforehand, especially if you're already on other types of medication.



References


1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286657/ | Practical Use and Risk of Modafinil, a Novel Waking Drug - Dongsoo Kim


2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761173/ | Modafinil in the treatment of excessive sleepiness


3. https://www.ncbi.nlm.nih.gov/pubmed/16171291 | Modafinil for treatment of residual excessive sleepiness in nasal continuous positive airway pressure-treated obstructive sleep apnea/hypopnea synd... - PubMed - NCBI


4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/ | Mechanisms of modafinil: A review of current research - Paul Gerrard and Robert Malcolm


5. https://www.ncbi.nlm.nih.gov/pubmed/16885432 | Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates the transporters and trace amine activity in vitro. - PubMed - NCBI


6. https://www.ncbi.nlm.nih.gov/pubmed/17920581 | Involvement of central histaminergic systems in modafinil-induced but not methylphenidate-induced increases in locomotor activity in rats. - PubMed - NCBI


7. https://www.sciencedirect.com/science/article/pii/S0304394001025526 | The effect of orexin-A and -B on the histamine release in the anterior hypothalamus in rats - Tomoko Ishizuka, Yumiko Yamamoto, Atsushi Yamatodani


8. https://www.ncbi.nlm.nih.gov/pubmed/23934211 | The neurobiology of modafinil as an enhancer of cognitive performance and a potential treatment for substance use disorders. - PubMed - NCBI


9. https://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects | Modafinil Side Effects by Likelihood and Severity


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